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Hypergraph-Based Doubly Robust Estimation for Causal Inference of Drug Combination Effects in Heart Failure Treatment

2025-12-16 health informatics Title + abstract only
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AO_SCPLOWBSTRACTC_SCPLOWDisease management for heart failure with preserved ejection fraction (HFpEF) requires understanding the comparative effectiveness of real-world drug combinations rather than single agents. Standard randomized controlled trials (RCTs) for multi-drug regimens are prohibitively expensive, slow, and often infeasible at scale, motivating the use of causal machine learning methods on large-scale electronic health records (EHRs). However, reliable estimation of treatment effect...

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