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Role of contralesional cortico-reticulospinal tract compensation in walking recovery after stroke

2025-12-15 rehabilitation medicine and physical therapy Title + abstract only
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PurposeEvidence suggests the contralesional cortico-reticulospinal tract (cCRST) upregulates after stroke, and that this upregulation correlates with worse motor function, suggesting it may be harmful for walking recovery. However, this relationship may be confounded by the extent of ipsilesional corticospinal tract (CST) and CRST damage, which could cause both greater cCRST upregulation and worse walking function. No previous studies have tested whether this confounding relationship exists, nor...

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