Low levels of systemic inflammation in asymptomatic TB detected during community-based screening in rural South Africa
Mtshali, L. N.; Olivier, S.; Fehr, J.; Zulu, T.; Gareta, D.; Baisley, K.; Hanekom, W. N.; Ndung'u, T.; Leslie, A.; Wong, E. B.
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Asymptomatic TB represents half of prevalent TB yet frequently remains undetected. We assessed the performance of plasma IL-6 and CRP as diagnostic biomarkers for asymptomatic TB identified by community-based screening. Both proteins were elevated in asymptomatic TB compared to community controls, but neither performed well as a diagnostic biomarker.
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