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Pulsatile Brain Motion as a Marker of Brain Aging and Dementia: Insights from 3D q-aMRI
2025-12-11
radiology and imaging
Title + abstract only
View on medRxiv
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Heart-brain interactions, including cardiac-induced brain pulsatility, are thought to support brain homeostasis, yet their alteration with aging and neurodegeneration remains poorly understood. Here, we used three-dimensional quantitative amplified MRI (q-aMRI) to visualize and quantify cardiac-induced pulsatile brain motion across healthy individuals and those on the Alzheimers and Lewy body disease spectra. Expert evaluations revealed consistent distinctions between normal and abnormal motion ...
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