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The effects of trauma on neurobiological and psychopathological phenotypes in a transdiagnostic community sample
2025-12-11
psychiatry and clinical psychology
Title + abstract only
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Trauma is an established risk factor for a diverse range of psychiatric disorders. This effect on risk is widely thought to be mediated, at least partially, by the deleterious impact of trauma on brain structure and function. We tested this neurobiological mediation hypothesis in 670 adults (40% male; age 18-45 years, M = 29.60, SD = 7.67) with diverse psychiatric histories who undertook self-reported and interview-based assessment of psychopathology along with magnetic resonance imaging (MRI). ...
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