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Oral potassium lowers clinic BP in untreated primary hypertension meta-analysis

2025-12-09 cardiovascular medicine Title + abstract only
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BackgroundPotassium has biologic plausibility to lower blood pressure (BP) via natriuresis, vascular effects, and RAAS modulation. The clinical effect in untreated primary hypertension remains uncertain. ObjectivesTo estimate the effect of oral potassium supplementation on clinic and 24-h ambulatory BP (ABPM) and to summarize safety. MethodsWe included randomized trials (parallel or crossover) in adults ([≥]18 y) with untreated primary hypertension comparing oral potassium supplements vs pl...

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