New observations on non-coding RNAs involved in the dual translation system in zebrafish development.
Breit, T. M.; Pagano, J. F. B.; van der Jagt, P. L.; Mittring, E.; Ensink, W. A.; van Olst, M.; van Leeuwen, S.; de Leeuw, W. C.; Nehrdich, U.; Spaink, H. P.; Rauwerda, H.; Dekker, R. J.
Show abstract
Cellular translation relies heavily on the involvements of several types of non-coding RNAs. In previous studies we have identified a dual translation system in zebrafish development, involving maternal-type and somatic-type rRNAs, snoRNAs, and snRNAs. In this study we focused on several remaining non-coding RNAs involved in the translation system; tRNAs, RNase P, and SRP RNA. Even though our studies have been limited in extent, for all three types of non-coding RNA we were able to identify a maternal-specific type, with substantial sequence differences as compared to the somatic-type variant. Hence, these RNA types complement the previously discovered RNA types in the unique dual translation system in zebrafish development.
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