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Co-Increasing Neuronal Noise and Beta Power in the Developing Brain

He, W.; Donoghue, T.; Sowman, P. F.; Seymour, R. A.; Brock, J.; Crain, S.; Voytek, B.; Hillebrand, A.

2019-11-12 neuroscience
10.1101/839258 bioRxiv
Show abstract

Accumulating evidence across species indicates that brain oscillations are superimposed upon an aperiodic 1/f - like power spectrum. Maturational changes in neuronal oscillations have not been assessed in tandem with this underlying aperiodic spectrum. The current study uncovers co-maturation of the aperiodic component alongside the periodic components (oscillations) in spontaneous magnetoencephalography (MEG) data. Beamformer-reconstructed MEG time-series allowed a direct comparison of power in the source domain between 24 children (8.0 {+/-} 2.5 years, 17 males) and 24 adults (40.6 {+/-} 17.4 years, 16 males). Our results suggest that the redistribution of oscillatory power from lower to higher frequencies that is observed in childhood does not hold once the age-related changes in the aperiodic signal are controlled for. When estimating both the periodic and aperiodic components, we found that power increases with age in the beta band only, and that the 1/f signal is flattened in adults compared to children. These results suggest a pattern of co-maturing beta oscillatory power with the aperiodic 1/f signal in typical childhood development.

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