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A Hierarchical Model of the Hypothalamo-Adreno-Pituitary syste

la Rota, C.; Vuza, D. T.; Haulica, A.

2019-11-11 systems biology
10.1101/837724 bioRxiv
Show abstract

We present a model of the Hypothalamo-Adreno-Pituitary (HPA) system; our approach is hierarchical and biologically sound, reflecting the complexity of the real HPA system. The structure of the conceptual model is based on theoretical frameworks of biological complex systems and its implementation takes advantage of recent hybrid automata modelling and analysis tools, being modular and reflecting parameter and mechanisms uncertainties.

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