Characterization of vertically and cross-species transmitted viruses in the cestode parasite Schistocephalus solidus
Hahn, M. A.; Rosario, K.; Lucas, P.; Dheilly, N. M.
Show abstract
Parasitic flatworms (Neodermata) represent a public health and economic burden due to associated debilitating diseases and limited therapeutic treatments available. Despite their importance, there is scarce information regarding flatworm-associated microbes. We report the discovery of six RNA viruses in the cestode Schistocephalus solidus. None were closely related to classified viruses and they represent new taxa. Mining transcriptomic data revealed the broad distribution of these viruses in Alaskan and European S. solidus populations. We demonstrate through in vitro culture of S. solidus that five of these viruses are vertically transmitted. With experimental infections and field-sampling, we show that one of the viruses is transmitted to parasitized hosts. The impact of these viruses in parasite fitness and pathogenicity, and in host-parasite co-evolutionary dynamics remains to be determined. The detection of six novel viruses in this first characterization of viruses in Neodermatans likely represents a fraction of virus diversity in parasitic flatworms.
Matching journals
The top 7 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Viral surveillance of invasive mammals in New Zealand reveals unique viral lineages reflecting their introduction history 97%
- Diversity of sea star-associated densoviruses and transcribed endogenized viral elements of densovirus origin 97%
- Characterization of Mollivirus kamchatka, the first modern representative of the proposed Molliviridae family of giant viruses 96%
Similar papers in this journal
- Viral metagenome characterization reveals species-specific virome profiles in Triatominae populations from the southern United States 97%
- Population genomics of louping ill virus provide new insights into the evolution of tick-borne flaviviruses 94%
- Paramyxoviruses in Old World fruit bats (Pteropodidae): an open database and synthesis of sampling effort, viral positivity, and coevolution 94%
Similar papers in this journal
Similar papers in this journal
- Emerging viruses in British Columbia salmon discovered via a viral immune response biomarker panel and metatranscriptomic sequencing 96%
- Ambecovirus, a novel Betacoronavirus subgenus circulating in neotropical bats sheds new light on bat-borne coronaviruses evolution 96%
- Diving Deep into Fish Bornaviruses: Uncovering Hidden Diversity and Transcriptional Strategies through Comprehensive Data Mining 95%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.