A comparison of long-term mortality associated with pathologic placental separation: highlighting possible trends and mechanisms
Jasani, S.; Demiray, A.; Stevenson, J.; Krawiec, C.
Show abstract
Abruption and retention, two types of abnormal placental separation, are associated with significant morbidity and mortality. Though advancements in obstetric management have improved peripartum injury, patients who experience abnormal placental separation may be at risk for long-term complications. This study evaluates long-term mortality in patients with abruption or retention compared to those with normal placental separation. When controlling for demographic factors, covariates and short-term mortality events, long-term mortality remained significantly elevated in the retention group and was lost in the abruption group. A variety of health outcomes were associated with either abruption, retention or in both abnormal placental separation groups. More research is needed to understand the mechanisms associated with abnormal placental separation and contributors to long-term mortality.
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