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Full BLOOD count TRends for colorectal cAnCer deteCtion (BLOODTRACC): external validation of colorectal cancer prediction models in English primary care

2025-11-27 oncology Title + abstract only
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IntroductionColorectal cancer has low survival rates when diagnosed late-stage. We previously developed sex-specific dynamic risk prediction models utilising trends in the full blood count (FBC), a blood test commonly performed in primary care, to support early detection. We aimed to externally validate these prediction models. MethodsWe performed a hybrid case-control and cohort study of patients with at least one FBC test. We first excluded FBCs within two years before diagnosis (cases) or st...

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