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Causation Between Smoking Quantity and Depressive Symptoms in Young Adults: Evidence from Novel Cross-Lagged Twin Models

2025-11-19 psychiatry and clinical psychology Title + abstract only
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BackgroundSmoking and depression often co-occur in young adults, potentially due to reciprocal causal effects and/or shared underlying etiological factors. Here, we tested causal hypotheses between smoking quantity (cigarettes per day; CigDay) and depressive symptoms (DepSx) using novel Biometrical Cross-Lagged Panel Models (CLPMs), which integrate twin developmental and direction-of-causation analyses for more robust causal inference in longitudinal twin studies. MethodsStudy sample included 1...

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