Back

Impact of Genetic Risk Factors on Coronary Heart Disease Risk Across the Age Spectrum in Three Major Race/Ethnicity Groups in the United States

2025-11-15 cardiovascular medicine Title + abstract only
View on medRxiv
Show abstract

BackgroundMeasures of genetic predisposition can improve prediction of risk of cardiometabolic diseases but more data is needed in groups under-represented in genomics research. In this study, we investigated the impact of genetic risk factors for coronary heart disease (CHD) - polygenic risk, monogenic risk [in the form of familial hypercholesterolemia (FH)], and family history (FamHx) - on CHD risk estimates, across the age spectrum, in two diverse cohorts of US adults - eMERGE IV (eIV) and Al...

Predicted journal destinations

1
Circulation: Genomic and Precision Medicine
30 training papers
#1 24.6%
2
Journal of the American Heart Association
92 training papers
Top 0.2% 24.6%
3
Circulation
37 training papers
Top 0.8% 10.3%
4
Frontiers in Cardiovascular Medicine
33 training papers
Top 4% 4.3%
5
PLOS ONE
1737 training papers
Top 84% 4.3%
6
eLife
262 training papers
Top 18% 2.1%
7
Atherosclerosis
16 training papers
Top 1.0% 2.1%
8
Open Heart
18 training papers
Top 4% 2.1%
9
BMC Medicine
155 training papers
Top 10% 2.1%
10
PLOS Medicine
95 training papers
Top 3% 2.1%
11
Scientific Reports
701 training papers
Top 77% 2.1%
12
Nature Communications
483 training papers
Top 41% 1.7%
13
Hypertension
20 training papers
Top 3% 1.7%
14
BMJ Open
553 training papers
Top 52% 1.7%
15
The American Journal of Cardiology
15 training papers
Top 4% 1.7%
16
European Heart Journal - Digital Health
15 training papers
Top 4% 1.5%
17
Heart Rhythm
16 training papers
Top 5% 0.8%
18
Nature Genetics
72 training papers
Top 10% 0.8%
19
International Journal of Epidemiology
65 training papers
Top 11% 0.8%
20
Journal of Clinical Medicine
77 training papers
Top 27% 0.5%
21
Nature Medicine
88 training papers
Top 24% 0.5%
22
The Lancet Digital Health
25 training papers
Top 3% 0.5%
23
Communications Medicine
63 training papers
Top 10% 0.5%
24
International Journal of Obesity
17 training papers
Top 3% 0.5%