Back

Healthcare utilization and cost impact of telehealth-delivered nutrition therapy for type 2 diabetes and obesity: a retrospective claims-based study

Shanmugam, P.; Adams, R. N.; Athinarayanan, S.; Wolfberg, A.; Ballreich, J.

2025-11-11 health economics
10.1101/2025.11.09.25339829 medRxiv
Show abstract

Structured AbstractO_ST_ABSImportanceC_ST_ABSType 2 diabetes and obesity drive substantial morbidity and spending. Rigorous evidence on the impacts of digitally delivered lifestyle interventions on healthcare cost and utilization are critical to assessing their value. ObjectiveDetermine the impact of a telehealth-delivered individualized nutrition therapy (INT) program on per-member-per-month (PMPM) total cost of care and utilization over one and two years. DesignRetrospective propensity score matched difference-in-differences analysis of cost and utilization outcomes over the study period of January 2016-March 2025. SettingUS adults participating in a telehealth T2D and obesity management program. ParticipantsEnrolled in INT for >1 day or had PCP visit for T2D or obesity during study period; had [&ge;]12 months pre-index and [&ge;]90 days post-index claims coverage (allowing [&le;]30-day gaps). Final matched sample: 6,580 participants and 6,580 controls (per arm: 3,819 with type 2 diabetes and 2,761 with obesity). ExposuresTelehealth-delivered, continuous care integrating individualized carbohydrate-reduced nutrition support, clinician-guided medication management, health coaching, and remote biometric monitoring. Main Outcomes and MeasuresOutcomes included PMPM allowed inpatient, outpatient, and prescription medication costs, inpatient, emergency department, primary care, cardiology, and endocrinology visits. For the T2D cohort, PMPM spending and proportion of days covered for each T2D medication. ResultsAmong 3,819 adults with T2D and 2,761 adults with obesity, program participation was associated with $240 and $256 PMPM reductions in the total cost of care at 12 months (-$230 and $189 over 24 months, all P<.001). In the T2D cohort, savings were driven by deprescription of SGLT2 inhibitors (66.8% reduction in PMPM cost), sulfonylureas (51.7%), insulin (43.9%), and GLP-1s (32.2%). In the obesity cohort, reductions accrued across inpatient, outpatient and prescription medication settings. Conclusions and RelevanceIn this large, real-world analysis, a nutrition-first digital care model was associated with sustained reductions in cost and utilization over 12-24 months, with immediate prescription medication cost reductions in the cohort with T2D and broader savings in the cohort with obesity. Together with prior clinical evidence, these findings suggest alignment of clinical effectiveness and cost reductions of a telehealth-delivered lifestyle intervention. Key pointsO_ST_ABSQuestionC_ST_ABSIs participation in a telehealth-delivered individualized nutrition therapy program associated with changes in healthcare costs and utilization among adults with type 2 diabetes (T2D) or obesity? FindingsIn this retrospective cohort study of 13,000 matched adults, participation was associated with lower total cost of care at one year (-$240 and -$256 for adults with T2D and obesity respectively) and over two years (T2D: -$230; obesity: $-189). Among adults with T2D, reductions were driven by inpatient costs and all T2D medications, including GLP-1s. Among adults with obesity, reductions occurred across inpatient, outpatient, and prescription medication costs. MeaningTelehealth-delivered nutrition therapy may reduce healthcare spending for adults with T2D or obesity.

Matching journals

The top 8 journals account for 50% of the predicted probability mass.

1
BMJ Open
554 papers in training set
Top 2%
10.1%
2
PLOS Medicine
98 papers in training set
Top 0.2%
10.1%
3
PLOS ONE
4510 papers in training set
Top 22%
8.4%
4
Public Health Nutrition
14 papers in training set
Top 0.1%
7.2%
5
The Lancet Healthy Longevity
11 papers in training set
Top 0.1%
6.3%
6
BMC Health Services Research
42 papers in training set
Top 0.6%
3.6%
7
American Journal of Preventive Medicine
11 papers in training set
Top 0.1%
3.6%
8
Preventive Medicine Reports
14 papers in training set
Top 0.1%
3.6%
50% of probability mass above
9
Diabetes, Obesity and Metabolism
17 papers in training set
Top 0.2%
2.4%
10
Clinical Infectious Diseases
231 papers in training set
Top 2%
2.1%
11
Journal of Medical Internet Research
85 papers in training set
Top 2%
1.9%
12
Diabetologia
36 papers in training set
Top 0.5%
1.8%
13
Nutrients
64 papers in training set
Top 0.9%
1.8%
14
BMC Medicine
163 papers in training set
Top 3%
1.8%
15
BMJ Open Diabetes Research & Care
15 papers in training set
Top 0.6%
1.7%
16
Medical Decision Making
10 papers in training set
Top 0.1%
1.7%
17
eClinicalMedicine
55 papers in training set
Top 0.6%
1.7%
18
Addiction
25 papers in training set
Top 0.3%
1.7%
19
BJGP Open
12 papers in training set
Top 0.4%
1.3%
20
Journal of Medical Economics
10 papers in training set
Top 0.1%
1.3%
21
BMJ
49 papers in training set
Top 0.7%
1.3%
22
Vaccine
189 papers in training set
Top 2%
0.9%
23
Diabetes Care
12 papers in training set
Top 0.2%
0.9%
24
Frontiers in Medicine
113 papers in training set
Top 6%
0.9%
25
Healthcare
16 papers in training set
Top 1%
0.9%
26
Public Health
34 papers in training set
Top 2%
0.8%
27
JAMA Network Open
127 papers in training set
Top 4%
0.8%
28
PLOS Global Public Health
293 papers in training set
Top 6%
0.7%
29
European Journal of Public Health
20 papers in training set
Top 1%
0.7%
30
Nature Human Behaviour
85 papers in training set
Top 5%
0.7%