Breaking the ''one nucleus, one whole genome'' rule: Neurospora crassa separates its haploid chromosomes into different nuclei
Tan, J.; Xu, Y.; Tian, L.; Chen, X.; Fischer, M.; Zhang, Y.; Li, X.
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Neurospora crassa has long served as a key fungal genetics model, facilitating discoveries like the "one gene, one enzyme" hypothesis. It produces many conidia, mostly with two or three nuclei and each nucleus was once thought to contain a full haploid genome. Using flow cytometry and FISH, we found that N. crassa haploid chromosomes are divided among nuclei, each conidium is haploid - challenging the "one nucleus, one whole genome" rule.
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