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Magnetocardiography can detect ventricular arrhythmia after myocardial ischemia

Ghahremani Arekhloo, N.; Parvizi, H.; Mardani, M.; Sularz, A.; Alkhouli, M.; Heidari, H.; Nazarpour, K.

2025-11-06 cardiovascular medicine
10.1101/2025.11.04.25339469 medRxiv
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BackgroundVentricular tachyarrhythmias (VTAs) are a leading cause of sudden cardiac death after myocardial infarction (MI). Accurate risk stratification remains a clinical challenge, prompting interest in magnetocardiography (MCG) as a non-invasive diagnostic tool. ObjectiveThis systematic review aimed to evaluate the diagnostic utility of MCG in predicting post-MI VTAs, with particular attention to waveform morphology and variability. MethodsWe searched the PubMed, Scopus, Web of Science, and other databases for studies investigating the role of MCG in post-MI arrhythmic risk assessment, published until March 2025. Eighteen eligible studies were identified and synthesised. ResultsMCG-derived parameters, including temporal and spatial repolarisation heterogeneity (seven studies), late field characteristics (seven studies), and intra-QRS fragmentation (seven), were consistently reported as potential predictors of VTAs. However, most studies were limited by small cohorts, heterogeneous methodologies, and the absence of standardised diagnostic criteria. ConclusionMCG shows promise as a predictive modality for post-MI VTAs, though its clinical utility is currently constrained by methodological and scalability issues. Future developments in portable, low-cost sensors, large-scale datasets, AI-driven analytics, and quantum technologies may support wider clinical adoption and enable community-based monitoring, potentially transforming MCG into a practical tool for personalised, preventive cardiovascular care.

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