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Cytomegalovirus latency exacerbates cardiac inflammation and tissue remodeling after myocardial infarction

2025-10-29 cardiovascular medicine Title + abstract only
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BackgroundEpidemiological studies have consistently associated cytomegalovirus (CMV) seropositivity with adverse cardiovascular outcomes. However, the mechanisms by which CMV infection impacts pathophysiological mechanisms in the heart remain poorly understood. In this study, we sought to dissect how latent murine CMV infection impacts cardiac immune cell dynamics at steady-state and during post-myocardial infarction (MI) repair. MethodsExperimental MI studies were conducted in C57BL/6J mice pr...

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