Distributional invariance and proportional scaling in axonal conduction
Cohen, L. D.; Marom, S.
Show abstract
Conduction velocity along axons reflects geometric and biophysical influences whose joint statistical organization remains largely uncharacterized. Using high-resolution time-of-arrival measurements along hundreds of identified axonal branches in vitro, we quantified how propagation speed changes along trajectories. The ratio between terminal and initial velocities,{rho} = vend/vstart, follows a right-skewed distribution whose shape remains invariant across branch lengths, positions within neurons, and hierarchical aggregation levels. Local conduction profiles reveal a predominantly progressive deceleration along branches. These observations indicate a simple and robust statistical organization of slowdown, suggesting that proportional modulation of propagation speed is a consistent feature of axonal signaling in structurally variable substrates.
Matching journals
The top 4 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Chloride dynamics determine the optimal distribution of inhibitory synapses to minimise dendritic excitability 94%
- Impact on backpropagation of the spatial heterogeneity of sodium channel kinetics in the axon initial segment 94%
- Ephaptic coupling in white matter fibre bundles modulates axonal transmission delays 93%
Similar papers in this journal
- Annihilation of action potentials induces electrical coupling between neurons 94%
- Using subthreshold events to characterize the functional architecture of electrically coupled networks 92%
- Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks 92%
Similar papers in this journal
Similar papers in this journal
- Single-cell Ca2+ parameter inference reveals how transcriptional states inform dynamic cell responses 90%
- Disentangling the Behavioural Variability of Confined Cell Migration 90%
- Morphological determinants of bite force capacity in insects: a biomechanical analysis of polymorphous leaf-cutter ants 90%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.