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Forecasting COVID-19 cases in US states using reconstructed incidence data

Nash, R. K.; Bhatia, S.; Wardle, J.; Cori, A.; Nouvellet, P.

2025-10-21 public and global health
10.1101/2025.10.20.25338346 medRxiv
Show abstract

Branching process models are commonly used in infectious disease forecasting and often rely on daily incidence data, but their utility can be restricted if incidence is not reported daily or if reporting becomes less frequent during prolonged outbreaks. In this study, an Expectation Maximisation algorithm is used to reconstruct the daily incidence of COVID-19 cases from weekly case counts. Using data from 13 US states that maintained mostly daily reporting of COVID-19 cases from March 2020 to February 2022, we evaluate forecasting performance by comparing models using the true daily incidence with those using reconstructed daily incidence. Our results show that forecasts generated from reconstructed incidence perform equally well as those generated using true daily incidence. These findings demonstrate the viability of using reconstructed incidence data for real-time forecasting, which could be particularly useful in scenarios where maintaining daily reporting is unsustainable or in settings with limited surveillance capacity.

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