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Surface Markers on Supermeres Outperform Extracellular Vesicles in Cancer Diagnosis
2025-10-07
oncology
Title + abstract only
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Extracellular nanocarriers, such as extracellular vesicles (EVs), lipoproteins, supermeres, and exomeres are diverse lipid-protein-nucleic acid assemblies. Among them, supermeres hold significant diagnostic potential but are challenging to characterize due to limited surface biomarker information and labor-intensive isolation methods. This study introduces an isolation-free Ion Exchange Membrane Sensing method for detection of supermeres within 30 minutes using 50 L of sample, with a sensitivity...
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