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Closed-Loop, Subgaleal Intersectional Short-Pulse Stimulation for the Treatment of Therapy-Resistant Epilepsy in Adults

2025-10-05 neurology Title + abstract only
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One-third of epilepsy patients do not fully respond to antiseizure medications (ASM), are not candidates for curative surgical interventions, or have unsuccessful surgical therapies. Safe and effective therapies remain limited for these treatment-resistant epilepsy (TRE) patients. Several palliative neurostimulation devices were approved by the US Food and Drug Administration (FDA) and other regulatory agencies: vagus nerve stimulation (VNS), responsive neurostimulation (RNS), and deep brain sti...

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