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A Pilot Study of Transcranial Magnetic Stimulation and the Right Teaching Parietal Junction

Skowron, M.; Morante, A.; Alvarez, A.; Keenan, J. P.

2025-09-17 neuroscience
10.1101/2025.09.15.676361 bioRxiv
Show abstract

Theory of Mind (ToM) is conceptualized as the ability to infer the thoughts and feelings of others. Many studies have found that ToM abilities play a central role in collaborative communication between adults, with teachers performing more effectively when they have high levels of ToM. One of the main brain regions implicated in ToM is the right temporoparietal junction (rTPJ), which is thought to be responsible for evaluating a persons belief formation process. The current study had participants engage in a Lego model building task consisting of a director who instructed a builder on how to create duplicate models from a prototype that only the director could see. The rTPJ of the director was targeted for excitatory (10 Hz) transcranial magnetic stimulation (TMS) and inhibitory (1 Hz) TMS. There was a trend such that there was a decrease in the amount of time needed and an increase in accuracy between excitatory TMS and sham TMS (the control). The opposite pattern was observed between inhibitory TMS and sham TMS. These results suggest that teaching abilities are likely at least partially dependent on the rTPJ.

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