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From Chewing to Chirping: The Misophonia Audiovisual Trigger Archive (MATA)

Oh, S.; Palmer, K.; Sabatina, D.; Pietrini, A.; O'Reilly, C.; Shinkareva, S.

2025-09-15 neuroscience
10.1101/2025.09.09.675007 bioRxiv
Show abstract

Misophonia is an emerging condition in which everyday sounds, such as chewing, sniffing, or tapping, evoke disproportionately intense emotional and physiological responses. Despite growing recognition of its clinical significance, progress in understanding misophonia has been hindered by the limited availability of standardized and ecologically valid stimulus sets. Here, we present a large, open-access archive of 1,300 five-second audiovisual clips spanning 12 empirically validated categories of misophonic triggers. This resource extends beyond orofacial movement-related sounds to include a diverse array of real-world triggers, and its audiovisual format enables systematic investigation of how visual context shapes responses to misophonic sounds. The archive lowers the barrier for laboratories to study misophonia, promotes reproducibility across sites, and offers applications ranging from crowdsourced assessments of population-level sensitivities to machine learning approaches for automated trigger detection. By providing the largest and most diverse audiovisual misophonia stimulus repository to date, this resource is designed to accelerate mechanistic, clinical, and translational research on misophonia and related sensory-emotional phenomena.

Published in Scientific Data (predicted rank #5) · training set

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