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Genomic privacy risks in GWAS summary statistics

2025-09-12 genetic and genomic medicine Title + abstract only
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The rapid advancement in sequencing technologies has exponentially increased the availability of genomic data, heightening concerns about data privacy. Despite the perceived safety of publicly accessible genome-wide association study (GWAS) summary statistics, we demonstrate that their combination with less sensitive high-dimensional phenotype data can lead to significant leakage of confidential genomic information. By transforming a linear regression model into linear programming constraints, w...

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