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Interplay of Generation Time and Spatial Structure in Epidemic Dynamics and the Reliability of Reproduction Ratio Estimates

2025-09-04 epidemiology Title + abstract only
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The reproduction ratio R is a central metric for monitoring infectious disease epidemics and guiding public health interventions. It is typically inferred from population-level surveillance data, but such estimates can be biased by the spatial structure of the underlying population and by complexities in disease natural history. Here, we develop a theoretical framework to study how the distribution of the generation time (the time from primary to secondary infection) interacts with spatial netwo...

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