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Demographic and Clinical Correlates of Discordant QuantiFERON TB Gold Tuberculosis Screening Results in a Low Endemicity Setting
2025-09-05
infectious diseases
Title + abstract only
View on medRxiv
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Interferon-{gamma} Release Assays (IGRAs), such as the QuantiFERON-TB Gold Plus (QFTTB) and T-SPOT.TB, are commonly used to detect prior exposure to Mycobacterium tuberculosis complex (Mtb), the causative agent of tuberculosis (TB). IGRA positive (IGRA+) asymptomatic individuals are diagnosed with presumed latent tuberculosis infection (LTBI) and often offered therapy to prevent progression to active disease. However, discordant results during serial or confirmatory IGRA testing pose challenges ...
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