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Interim Analysis of Dose-Escalated Preoperative Breast Irradiation: A Phase Ib study

2025-09-02 oncology Title + abstract only
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IntroductionBreast irradiation (RT) is often recommended as part of breast conservative therapy (BCT) and is often delivered daily over multiple weeks after breast conserving surgery (BCS). Information regarding tumor response is lost when BCS is performed before oncologic treatment. Short course partial breast irradiation delivered preoperatively (PRT) is a potential solution. MethodsFollowing informed consent, ten participants enrolled in one of four cohorts of HCC 22-003 (NCT05464667). Each ...

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