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Tracking Student Wellbeing Throughout the COVID-19 Pandemic

Noble, D. J.; Raison, C. L.

2025-09-02 public and global health
10.1101/2025.08.29.25334729 medRxiv
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BackgroundThe COVID-19 pandemic served as a global, uncontrolled social isolation experiment, with especially pernicious effects on mental health in young adults. We sought to understand how the COVID-19 pandemic and associated social restrictions impacted the wellbeing of university undergraduate students. Methods277 total U.S. undergraduate students enrolled in a course on mental wellbeing and resilience that was offered once each year from 2020 to 2024. Students anonymously completed surveys of anxiety, depression, and wellbeing on a weekly basis. These behavioral data were aggregated and investigated for associations with local COVID-19 case levels and a university social gathering meter. ResultsAverage student wellbeing declined a few months into the COVID-19 pandemic in Fall 2020, remaining low in Fall 2021 and Spring 2022, with 63.7% of students at-risk for poor wellbeing based on standard cut-offs over these three semesters. Depression and anxiety peaked during Fall 2021 with 39.0% and 34.5% of students at-risk for anxiety and depressive disorders, respectively. Mental health gradually improved following the return to in-person learning in mid-Spring 2022. Over all five semesters, survey questions reflecting anhedonia strongly associated with social gathering restrictions whereas questions assessing acute anxiety most strongly associated with local COVID-19 case levels. ConclusionsOur findings highlight the negative impact of the COVID-19 pandemic on university student wellbeing and suggest partially separable influences of COVID-19 infection prevalence and social isolation on levels of student anxiety and anhedonia. More research is needed to minimize the mental costs of future pandemics in an increasingly interconnected world.

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