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Exploring trade-offs in diagnostic algorithm, population coverage, and duration of community screening for tuberculosis

2025-08-26 public and global health Title + abstract only
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BackgroundCurrent tuberculosis (TB) prevention and care strategies have failed to reduce disease burden at the pace required to meet global targets. Community screening may enable more rapid declines in TB burden, but evidence is limited. We used mathematical modelling to evaluate trade-offs in diagnostic algorithm, population coverage, and duration of screening. Methods and FindingsWe used a TB model, which recognised symptomatic and asymptomatic infectious TB (defined by whether an individual...

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