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Myo-Inositol Concentration in the Medial Prefrontal Cortex is Associated with Changes in Brain White Matter Microstructure in Early Psychosis

2025-08-21 psychiatry and clinical psychology Title + abstract only
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Recent research highlights the critical role of white matter (WM) alterations in psychosis and schizophrenia (SZ), reporting volumetric and structural brain changes in affected individuals. In this study, we explored the role of astroglia in SZ, which is believed to play a role in white matter integrity. We investigated for the first time the associations between advanced diffusion Magnetic Resonance Imaging (dMRI) measures of WM microstructure, and Magnetic Resonance Spectroscopy (MRS)-derived ...

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