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Complement expression in human atherosclerotic plaques and blood cells in patients with coronary artery disease
2025-08-12
cardiovascular medicine
Title + abstract only
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BackgroundInflammatory processes are a key cause of atherosclerosis and cardiovascular diseases. Complement system has been implicated but evidence is less clear. We tested whether atherosclerosis severity, plaque types, and vascular region are associated with mRNA expression of genes encoding proteins of the complement system and investigated the cell-specific expression of the most differentially expressed transcripts in plaque macrophages, fibroblasts, and endothelial, smooth muscle, Schwann,...
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