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Pilot Randomized Trial of Two Food Purchasing Interventions in Hypertensive Individuals in New Orleans: An American Heart Association Food is Medicine Initiative

Tannu, M.; Young, R.; Brucker, A.; Simon-Friedt, B.; Bisyuk, Y.; Tumusiime, S.; Rudov, L.; Stein, J.; Alley, M.; Hannigan, D.; Young, M.; McGary, J.; Palmer, S.; Cohen, L.; Pagidipati, N. J.; Hernandez, A. F.; Carton, T.

2025-08-05 cardiovascular medicine
10.1101/2025.08.01.25332844 medRxiv
Show abstract

BackgroundConsuming fruits and vegetables daily is linked to improved health in individuals with hypertension, yet access to nutritious foods remains limited. Voucher incentives have been shown to improve healthy food purchasing. ObjectiveCompare the effects of an online versus in-store voucher intervention on food purchasing and health outcomes in hypertensive individuals. MethodsIn this randomized, pilot trial, 98 participants with uncontrolled hypertension received a $100 monthly food voucher to either an online grocery platform or an in-store local grocery. Both groups received educational materials. The primary outcome was change in self-reported fruit and vegetable consumption. Secondary outcomes were voucher utilization, engagement with educational materials, and changes in BP, weight, and BMI. Generalized estimating equations for repeated measures were used to assess changes in food-group consumption over the five study months. ResultsThere was no statistically significant difference between arms for self-reported fruit and vegetable consumption. There was an overall 20% (IQR -17%, 93%) increase in fruit and vegetable consumption within both arms. Voucher utilization was significantly higher in the in-store arm (>90%) than the online arm (<64%). Engagement with educational materials was greater in the in-store arm. No significant changes in weight, BMI or BP were observed. ConclusionThere was no significant difference between in-store and online vouchers for fruit and vegetable consumption. Higher engagement and voucher utilization were observed in the in-store arm than the online arm. Future interventions should address technological barriers and be conducted in larger populations to enhance program effectiveness and assess long-term health impacts.

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