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Health and economic impact of introducing norovirus vaccination in England accounting for acute kidney injury: model-based cost-effectiveness analysis

2025-07-31 health economics Title + abstract only
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BackgroundNorovirus vaccines are currently undergoing advanced clinical trials. Acute kidney injury (AKI) is a serious sequelae of norovirus infection. This study evaluated the health and economic impact of implementing a norovirus vaccination programme in England and assessed the contribution of AKI. MethodsWe constructed a deterministic age-stratified dynamic-transmission compartmental model. Three single-dose norovirus vaccination strategies were compared to a no-vaccination strategy: target...

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