The CFII components PCF11 and Cbc change subnuclear localization as cells differentiate in the male germ line adult stem cell lineage
Nava, I.; Fuller, M. T.; Gallicchio, L.
Show abstract
Stage specific increased expression of PCF11 and Cbc, the two components of Cleavage Factor complex II, contribute to developmentally regulated 3UTR shortening due to alternate polyadenylation of nascent RNA molecules in Drosophila spermatocytes compared to spermatogonia. Here, we show that both Cbc and PCF11 change subnuclear localization during male germ cell differentiation, from homogeneous in the nucleus in spermatogonia and early spermatocytes to concentrated around the nucleolus in later spermatocyte stages.
Matching journals
The top 4 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- VCP acts downstream of tTAFs to downregulate mono-ubiquitinated H2A and promote spermatocyte differentiation in Drosophila 97%
- The intrinsically disordered protein SPE-18 promotes localized assembly of the major sperm protein in C. elegans spermatocytes 96%
- Castor is a temporal transcription factor that specifies early born central complex neuron identity 95%
Similar papers in this journal
- TRIP13 localizes to synapsed chromosomes and functions as a dosage-sensitive regulator of meiosis 96%
- Differential modifications of the C-terminal tails of α-tubulin isoforms and their importance for kinesin-based microtubule transport in vivo 96%
- A TOPBP1 Allele Causing Male Infertility Uncouples XY Silencing Dynamics From Sex Body Formation 96%
Similar papers in this journal
- Dynein light chain-dependent dimerization of Egalitarian is essential for maintaining oocyte fate in Drosophila. 95%
- The Caenorhabditis elegans spe-21 gene that encodes a palmitoyltransferase is necessary for spermiogenesis. 95%
- β-importins Tnpo-SR and Cadmus and the small GTPase Ran promote ovarian cyst formation in Drosophila 95%
Similar papers in this journal
Similar papers in this journal
- Germline Sex Determination regulates sex-specific signaling between germline stem cells and their niche 96%
- Simultaneous suppression of ribosome biogenesis and Tor activation by TRIM-NHL proteins promotes terminal differentiation 96%
- Defining the roles of the Integrator, NEXT, and nuclear exosome complexes in Drosophila oogenesis 95%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.