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Data Resource Profile: the Physical Activity Cohort Repository (PACe)

Boing, L.; Ramirez Varela, A.; Alomairah, S. A. M.; Bennett, D. A.; Bohn, L.; Hume, C.; Kontostoli, E.; Gudmundsdottir, S. L.; Mackie, P.; Mair, J. L.; Martins, C.; Mota, J.; Pizarro, A.; Rossen, J.; Tarp, J.; Tew, K.; von Rosen, P.; Boyle, T.; Lynch, B. M.

2025-07-23 epidemiology
10.1101/2025.07.22.25332023 medRxiv
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Key Features* The Physical Activity Cohort Repository (PACe) project created a searchable online database of cohort studies that have prospectively collected data on physical activity and/or sedentary behaviour (self-report and/or device-based measurement) at three or more timepoints. Only cohorts with [≥] 1,000 participants at baseline were included. * The PACe is a freely available resource created to encourage researchers to return to existing cohorts to apply contemporary causal inference methods that appropriately deal with time varying exposures and confounders, to improve the quality of evidence pertaining to physical activity, sedentary behaviour and health. * Two hundred and nineteen unique cohorts were included in the initial iteration of the PACe, representing all World Health Organization regions. The earliest included cohort started in 1922 (the Terman Life-Cycle Study) and extends to ongoing cohorts. * The development of the PACe was an international effort; this resource was designed to facilitate global collaboration and building research capacity in low- and middle-income countries. * We will update the repository every two years, to ensure that new cohorts and cohorts adding additional waves of follow-up are captured.

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