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Effect of Cardiac Fiber Orientation on Electrical Dyssynchrony in Ventricular Ectopy

2025-07-14 cardiovascular medicine Title + abstract only
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BackgroundWidened QRS complex confers worse prognosis in both pacing and premature ventricular contraction (PVC), and may predispose to heart failure. In healthy adult patients, cardiac fiber orientation is highly variable. While traversing the myocardial wall from epicardium to endocardium, helix angles are known to range between -90{degrees} and 90{degrees}. It is currently not well understood how the location of ectopy and variable epicardial and endocardial helix angle configurations interac...

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