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Mosaic loss of chromosome Y and coronary atherosclerosis in men: insights into sex differences in cardiovascular risk from the SCAPIS study
2025-07-14
cardiovascular medicine
Title + abstract only
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BackgroundAtherosclerosis predominantly affects men and is the underlying cause of coronary artery disease (CAD) and myocardial infarction (MI). Recent studies show that mosaic loss of chromosome Y (LOY) in blood is associated with all major causes of death, including CAD and MI. However, the relation between LOY and subclinical atherosclerosis remains unclear. This study aims to investigate associations between the male-specific LOY and atherosclerosis. MethodsTo examine associations between h...
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