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Classifying Chest Pain as Typical vs. Atypical Fails to Discriminate Acute Coronary Occlusion and Does Not Predict Mortality

2025-06-26 cardiovascular medicine Title + abstract only
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BackgroundWhether symptom descriptors meaningfully change post-test probability for occlusion myocardial infarction (OMI) in the emergency department (ED) remains uncertain, particularly when the reference standard is imperfect and may miss NSTEMI-OMI without ST elevation. MethodsWe retrospectively analyzed 13,262 ED encounters (2021-2025) with chest pain, ECG, and hs-cTnI testing. The index test was a legacy descriptor (type A/B vs C/D). The composite reference was door-to-balloon activation o...

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