Back

Genetic Contribution of Cardiorespiratory Fitness in Morbidity and Mortality: A Prospective FinnGen and HUNT study

2025-06-26 sports medicine Title + abstract only
View on medRxiv
Show abstract

ObjectivesTo quantify the contribution of cardiorespiratory fitness (CRF) genetics in common non-communicable disease (NCD) and mortality risk and to assess whether health discrepancies exist between "inherited" and "gained" CRF. MethodsWe used a validated SBayesR-based genome-wide polygenic score, leveraging information from 905,707 single-nucleotide polymorphisms, to measure CRF genetics (PGS CRF). Associations with register-based incident cardiovascular disease, cancer, pulmonary disease, ty...

Predicted journal destinations

1
PLOS ONE
1737 training papers
Top 54% 11.5%
2
BMJ Open
553 training papers
Top 20% 7.6%
3
Scientific Reports
701 training papers
Top 28% 7.6%
4
Nutrients
43 training papers
Top 1% 5.8%
5
Communications Biology
36 training papers
#1 5.4%
6
Journal of the American Heart Association
92 training papers
Top 7% 3.8%
7
International Journal of Environmental Research and Public Health
116 training papers
Top 6% 3.8%
8
PLOS Medicine
95 training papers
Top 2% 3.8%
9
JAMA Network Open
125 training papers
Top 6% 2.7%
10
eLife
262 training papers
Top 17% 2.7%
11
European Journal of Epidemiology
36 training papers
Top 0.5% 2.1%
12
Aging Cell
21 training papers
Top 0.7% 1.9%
13
BMC Medicine
155 training papers
Top 12% 1.9%
14
International Journal of Epidemiology
65 training papers
Top 4% 1.9%
15
Nature Communications
483 training papers
Top 38% 1.9%
16
Communications Medicine
63 training papers
Top 2% 1.5%
17
International Journal of Behavioral Nutrition and Physical Activity
15 training papers
Top 0.7% 1.5%
18
npj Digital Medicine
85 training papers
Top 13% 1.5%
19
The American Journal of Clinical Nutrition
16 training papers
Top 1% 1.3%
20
Genome Medicine
56 training papers
Top 6% 1.3%
21
BMC Public Health
148 training papers
Top 30% 0.7%
22
Alzheimer's & Dementia
84 training papers
Top 9% 0.7%
23
eBioMedicine
82 training papers
Top 13% 0.7%