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A critical role for brain nutrition in the life-history decisions of a partially migratory fish

Koene, J. P.; Jacobs, A.; Zavorka, L.; Pilecky, M.; Honkanen, H.; Kainz, M.; Elmer, K. R.; Adams, C.

2025-06-24 ecology
10.1101/2025.06.19.660559 bioRxiv
Show abstract

The role played by omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) in life-history polymorphisms in partially migratory species remains poorly understood. Yet, brain development is highly dependent upon nutrition, particularly the supply of n-3 LC-PUFA, derived from diet or internally converted from their shorter-chain precursors, and the fitness of animals may be shaped by cognitive performance, including effective spatial navigation required by migration. We investigated juveniles of a wild polymorphic population of brown trout, Salmo trutta, with three distinct migratory ecotypes, at the point of first outward migration. Using a combination of fatty acid contents, compound-specific stable isotope analysis, and liver transcriptomics, we found that non-migrants compensated for dietary deficiency by biosynthesising n-3 LC-PUFA from precursor molecules and routing them to cell membranes to a greater extent than did migrants. These findings highlight contrasting intake and processing between migratory and non-migratory life histories of nutrients associated with brain development.

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