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Focal Adhesion Kinase Variants May Contribute to Risk of Human Myelomeningocele
2025-06-12
genetic and genomic medicine
Title + abstract only
View on medRxiv
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Myelomeningocele (MMC) is the most severe form of an open neural tube defect (NTD) that is compatible with life. The prevalence of MMC in the United States is 1 in 2,500 live births, with the two ethnicities that have the highest occurrence of MMC being Mexican American (MA) and Caucasian American (EA). Research to date has shown that MMC results from a cumulative effect of environmental and genetic factors. Therefore, determining the underlying molecular etiology would be a step toward developi...
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