Patient Observational Pain and Activity Survey (POPAS) Study using Sequential Electrical Stimulator with Intersperse Technology in Chronic Axial Spine and Peripheral Joint Pain

ObjectiveChronic spine and joint pain are disabling conditions that are prevalent within the general population, but non-invasive and non-pharmacologic treatment options are limited. Sequential Electrical Stimulation (SES) with intersperse therapy is a novel non-invasive, non-pharmacologic technology utilizing a combination of high-frequency interferential therapy for pain relief and neuromuscular electrical stimulation (NMES) for muscle rehabilitation. This study aims to determine the real-world effectiveness of the SES with intersperse in the general population suffering from chronic spine and joint pain. DesignWe conducted a cohort study on general population participants with patient observational pain and activity surveys completed upon use of the SES with intersperse device (RS-4i(R) PlusTM) at 1-month, 3-month, and 6-month intervals. ResultsThe study results showed that among the 61 participants across all treatment groups, the device produced significantly reduced NRS pain scores and improved functional and activity outcomes. The results were consistent in short-term intervals and improved with long-term intervals. ConclusionThe novel SES with intersperse device can significantly reduce pain and improve the daily function of patients in the general population over a long treatment interval. This provides an effective non-invasive and non-pharmacologic treatment for chronic spine and joint pain.