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Seasonal Trends of COVID-19 Deaths in Italy: A Confirmatory Linear Regression Study with Time Series Data from 2024/2025

Roccetti, M.

2025-05-31 epidemiology
10.1101/2025.05.30.25328619 medRxiv
Show abstract

This study builds on and extends a previous research conducted with the time series data of COVID-19 deaths in Italy in the period 2021-2024. In those earlier works, weekly COVID-19 deaths showed pronounced seasonal increasing variations of COVID-19 mortality, rising in summer and high fall to peak in early winter, and then declining in the late winter and spring periods. Using a linear regression model, this current study has validated the seasonal mortality pattern mentioned before. We present original findings achieved with recent data from 53 weeks starting with the end of May 2024 until the end of May 2025. They confirm a recurring seasonal pattern of COVID-19 deaths, rising in early summer and peaking in high fall. Then, we document a steady decrease, starting in mid-winter until the end of the spring period. Since there is little published work from Italy in this context, having clearly shown the seasons with common increasing variations of COVID-19 mortality offers a contribution towards helping that subset of at risk population who are seasonally vulnerable. Our present study indicates that the COVID-19 mortality trend observed in previous years is still continuing, influenced by several factors that need further investigation.

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