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Drug Repurposing for Parkinson's Disease: A Large-Scale Multi-Cohort Study
2025-05-21
neurology
Title + abstract only
View on medRxiv
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BackgroundProgress in Parkinsons disease (PD) is hampered by two critical obstacles: the lack of disease-modifying drugs and the difficulty of identify individuals at early, prodromal disease stages for clinical trials. MethodsWe conducted a retrospective, multi-cohort study using data from the Mass General Brigham (MGB) Biobank for discovery and the Accelerating Medicines Partnership Parkinsons Disease (AMP-PD) program for replication. Logistic regression was used to estimate the associations ...
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