Back

cellSight: Characterizing dynamics of cells using single-cell RNA-sequencing

Chatterjee, R.; Gohel, C.; Shook, B. A.; Rahnavard, A.

2025-05-22 bioinformatics
10.1101/2025.05.16.654572 bioRxiv
Show abstract

Single-cell analysis has transformed our understanding of cellular diversity, offering insights into complex biological systems. Yet, manual data processing in single-cell studies poses challenges, including inefficiency, human error, and limited scalability. To address these issues, we propose the automated workflow cellSight, which integrates high-throughput sequencing in a user-friendly platform. By automating tasks like cell type clustering, feature extraction, and data normalization, cellSight reduces researcher workload, promoting focus on data interpretation and hypothesis generation. Its standardized analysis pipelines and quality control metrics enhance reproducibility, enabling collaboration across studies. Moreover, cellSights adaptability supports integration with emerging technologies, keeping pace with advancements in single-cell genomics. cellSight accelerates discoveries in single-cell biology, driving impactful insights and clinical translation. It is available with documentation and tutorials at https://github.com/omicsEye/cellSight.

Matching journals

The top 9 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.