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Moving beyond risk ratios in sibling analysis: estimating clinically useful measures from family-based analysis
2025-05-16
epidemiology
Title + abstract only
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ObjectiveFindings from family-based analyses, such as sibling comparisons, are often reported using only odds ratios or hazard ratios. We demonstrate how this can be improved upon by applying the marginalized between-within framework. Study Design and SettingWe provide an overview of sibling comparison methods and the marginalized between-within framework, which enables estimation of absolute risks and clinically relevant metrics while accounting for shared familial confounding. We illustrate t...
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