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A Tutorial on Discrete Event Simulation Models in R Using a Cost-Effectiveness Analysis Example

2025-05-16 epidemiology Title + abstract only
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Discrete Event Simulation (DES) is a flexible and computationally efficient approach for modeling diverse processes; however, DES remains underutilized in healthcare and medical decision-making due to a lack of reliable and reproducible implementations. We developed an open-source DES framework in R to simulate individual-level state-transition models (iSTMs) in continuous time accounting for treatment effects, time dependence on state residence, and age-dependent mortality. Our DES implementati...

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