Knowledge, Awareness, and Attitudes Toward Epilepsy in Palestine; A Cross-Sectional Study

BackgroundEpilepsy is a prevalent neurological disorder often surrounded by misinformation and stigma, especially in resource-constrained settings. Despite effective treatments, public misconceptions can hinder diagnosis, treatment adherence, and social inclusion. In Palestine, where cultural beliefs and healthcare access are shaped by complex socio-political factors, understanding public perceptions of epilepsy is vital. ObjectiveThis study aimed to assess the level of knowledge, awareness, and attitudes toward epilepsy among the Palestinian population and to identify sociodemographic factors influencing these domains. MethodsA cross-sectional survey was conducted from January to April 2025 using a structured, self-administered questionnaire distributed online. The sample included 570 Palestinian adults aged 18-65 years. Participants knowledge, awareness, and attitudes were evaluated using validated scoring systems. Statistical analyses included chi-square tests and multivariate logistic regression to determine predictors of positive outcomes. ResultsOverall, 52.1% of participants demonstrated good knowledge of epilepsy, 49.5% had good awareness, and 82.5% expressed positive attitudes toward individuals with epilepsy. Educational attainment, particularly at the postgraduate level, was the strongest predictor of good knowledge (OR = 5.60), good awareness (OR = 5.60), and positive attitude (OR = 4.38). Male gender was independently associated with lower awareness (OR = 0.59). Despite knowledge gaps, a broadly accepting public stance was observed. ConclusionWhile knowledge and awareness of epilepsy remain moderate in the Palestinian population, attitudes are overwhelmingly positive. Educational initiatives targeting knowledge deficits, especially among males and less-educated groups, can leverage this positive social foundation to reduce stigma and improve epilepsy care and inclusion. Tailored public health strategies are essential to promote accurate understanding and effective first-aid responses.