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Gene X Environment Interactions: Polygenic Scores and the Impact of a Early Childhood Intervention in Colombia

2025-05-11 health economics Title + abstract only
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We evaluate impacts heterogeneity of an Early Childhood Intervention in Colombia, with respect to the Educational Attainment Polygenic Score (EA4 PGS) constructed from DNA data based on GWAS weights from a European population. We find that the EA4 PGS is predictive of several measures of child development, mothers IQ and, to some extent, educational attainment. We also show that the impacts of the intervention are significantly greater in children with low PGS, to the point that the intervention...

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